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We constructed physical (PCS-36) and mental component summary (MCS-36) subscales and short-form-Links of London U Charm (SF-6D) health utility index for all DPP participants completing a baseline 36-item short form (SF-36) HRQL assessment (N=3,064). We used linear regression to test associations Links of London V Charm changes in body weight and changes in HRQL indicators, while adjusting for other demographic and behavioral variables. Overall differences in HRQL between treatment groups were highly statistically significant but clinically small after 1 year. In multivariable models, weight change was independently associated with change in SF-6D score (increase of 0.007 for every 5 kg weight loss; but treatment effects independent of Links of London W Charm loss were not. We found no significant interaction between baseline obesity severity and changes in SF-6D with changes in body weight. However, increases in physical function (PCS-36) with weight loss were greater in persons with higher baseline obesity severity. Current study results from the report, 'Changes in health state utilities with changes in body mass in the Diabetes Prevention Program,' Links of London Wide Purple And Pink Friendship Bracelet been published.